With over 20 easy-to-use template protocols for cleaning validation of extensively used equipments, this book provides technical solutions to assist in fulfilling the training needs of finished pharmaceutical manufacturers. Drawing on the authors’ more than two decades of experience, the text offers hands-on training based on current approaches and techniques. The manual is organized as a database to support those involved in the development, manufacturing, auditing, and validation of bio-pharmaceuticals on a pilot scale, that can lead to scaled-up production. It also provides exclusive training guidelines in a CD-ROM to enable the users to amend or adapt processes as necessary.
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Analysis & Pharmaceutical Quality
Biopharmaceutics
Reference

This volume discusses the physical and mathematical analysis of transport phenomena associated with food processing. The models presented describe many of the important physical and biological transformations that occur in food during processing. After introducing the fundamentals of heat, mass, and momentum transfer as well as computational fluid dynamics, the book focuses on specialized topics in food processing. It covers thermal, low temperature, non-thermal, and non-conventional thermal processing, along with the analysis of biological and enzyme reactors. The book also explores the use of artificial neural networks, exergy analysis, process control, and cleaning-in-place systems in industry.
• Contemporary Food Engineering
Industrial Chemistry
Product Development
Reference
Professional

Helping readers avoid common mistakes and build better models, this is one of the first books to apply the popular patterns perspective to database systems and the data models that are used to design state-of-the-art, efficient database systems. Best-selling author and database expert Dr. Michael Blaha provides detailed data model patterns as a basis for expertly building data models. Since most commercial software is built around a database, he focuses on databases rather than programming. He emphasizes how database representation sets the path for the software, determines its flexibility, affects its quality, and influences whether the software succeeds or fails.
• Database Systems and Applications
Algorithms & Complexity
Data Preparation & Mining
Reference

Understanding the molecular interactions responsible for chiral recognition is of primary importance in life chemistry. This volume describes the structural and energetic aspects of these interactions. Topics discussed include optical spectroscopy in jet-cooled conditions in neutral chiral molecules and complexes, and mass spectrometry approaches to chiral recognition in ionic complexes. These include the study of the stability of supramolecular chiral host-guest adducts, the study of chiral catalysts and chiral selectors, the use of small DNA sequences as auxiliaries for discriminating the enantiomers of amino-acids, and the probe of the chirality of a single amino acid within a peptide chain.
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Physical Chemistry
Organic Chemistry
Systems Biology
Reference
Professional

A comprehensive collection of seminal pieces on environmental criminology, this work focuses on the role that the immediate environment plays in the occurrence of a crime. Legendary contributors demonstrate that a careful analysis of environmental factors is key to understanding the causes of crime, solving crimes, and helping to predict and prevent them. Topics covered include routine activity theory, the geometric theory of crime, the rational choice theory, and the pattern theory of crime. The book also explores concepts related to crime prevention. This volume is invaluable as a textbook and as a professional reference.
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Forensic Science - Law
Textbook

A companion to Volume V: Applications of Ion Trapping Devices , this volume explores the latest advances in this expanding field. It covers new methods for trapping ions, such as the Orbitrap™, the digital ion trap, the rectilinear ion trap, and the toroidal ion trap; the development and application of the quadrupole ion trap and the quadrupole linear ion trap; and the introduction of high-field asymmetric waveform ion mobility spectrometry. The book explains all terms, acronyms, procedures, and equations in a style readily accessible at the graduate level and presents a common writing style that enables readers to appreciate the commonalities of topics.
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Chemical Spectroscopy
Analytical Chemistry
Reference
Professional

One of the most advanced and popular numerical computer models used in the field of soil physics, the HYDRUS series is used for the analysis of water flow and solute transport in variably saturated porous media. Co-authored by the software’s creator, Dr. Jirka Simunek, this volume demonstrates two-and three- dimensional simulations and computer animations of numerical models using the software. Classroom-tested at the University of Georgia, this volume includes numerous examples and homework problems. It provides students with access to the base HYDRUS program as well as the Rosetta Database, which contains large volumes of information on the hydraulic properties of soils.
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CRC/IHC Default Subject Code
Soil Mechanics
Condensed Matter Physics
Textbook
Undergraduate

In recent years, there has been increased understanding of the mechanisms involved in the transport of metal ions into and out of target cells, particularly epithelial cells. In addition, there have been significant advancements in the roles of certain metal ions in the conformational changes and function of cellular proteins. This volume explains the role of key biologically relevant divalent metal ions involved in the molecular and cellular biology of various target cell populations. Although it primarily focuses on homeostatic metals such as nickel, zinc, and chromium, the text also discusses a few environmentally relevant toxic divalent cations, including mercury, cadmium, and arsenic.
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Cell Biology
Molecular Biology
Toxicology
Reference
Professional

While still early in its development, cognitive radio is a highly promising communications paradigm that can effectively address the spectrum insufficiency problem. This book provides comprehensive technical and regulatory guidance across cognitive radio, cognitive wireless networks, and dynamic spectrum access. A one-stop reference written by those pioneering the field, it examines concepts, techniques, protocols, regulations, and standards, as well as recent progress and system implementations. It covers routing, Medium Access Control (MAC), cooperation schemes, resource management, mobility, and game theory approach.
• Wireless Networks and Mobile Communications
Digital & Wireless Communication
Telecommunications
Communications System Design
Reference
Professional

Rapid advancements in the application of soft computing tools and techniques have proven valuable in the development of highly scalable systems. Although many resources on the subject adequately cover the theoretic concepts, few provide clear insight into their practical application. Filling this need, this book explains such applications, including the underlying technology and its implementation. It covers the theoretical foundations of soft computing and supply a concise explanation of various models, principles, algorithms, tools, and techniques, including artificial neural networks, fuzzy systems, evolutionary algorithms, and hybrid algorithms.
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Software Engineering & Systems Development
Intelligent Systems
Intelligent Systems
Reference